Cost-effectiveness of distributing naloxone to heroin users for lay overdose reversal in Russian cities

The objective of this study was to evaluate the cost-effectiveness of distributing naloxone to illicit opioid users for lay overdose reversal in Russian cities. The research showed that naloxone distribution to heroin users for lay overdose reversal is highly likely to reduce overdose deaths in target communities and is robustly cost-effective, even within the constraints of this conservative model.

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