The US is in the midst of a major public health crisis. Tens of thousands of deaths are directly attributable to overdose over the past two decades and no end is in sight. Reeling from the failures of the “war on drugs”, many argue for new approaches grounded more firmly in public health and human centred drug policies. Join some of the world’s leading experts on this topic to learn how the US can learn the lessons of past policy failures and policies that provide greater hope to help end the overdose crisis.