This report presents an overview of infectious diseases among people who inject drugs in Europe, both in the community and in prison settings, covering disease surveillance, outbreak investigations, and prevention and control, for the period up to the end of February 2019. The report describes the population at risk, in terms of the number of injectors and the main injecting practices, presenting the latest data on incidence and prevalence of drug-related hepatitis C and B virus and HIV infections, as well as recent outbreaks, among people who inject drugs in Europe. This is accompanied by an overview of harm reduction intervention coverage, testing and treatment.