America’s opioid epidemic continues to cause unprecedented overdose deaths and fuel increases in new cases of hepatitis B and C, and HIV. According to the CDC, in 2016 over 64,000 people died of accidental overdose and over 60% of new hepatitis C cases and approximately 10% of new HIV cases were related to injection drug use. From 2004-2014 there was a 400% increase in acute hepatitis C among 18-29-year olds that is correlated with dramatic increases in heroin and prescription opioid injection. Overall, among people who inject drugs, prevalence of HCV is estimated to be as high as 80%. Hepatitis B is also increasing as a result of the opioid epidemic. From 2006-2013 the number of new hepatitis B infections in three states (Kentucky, Tennessee, and West Virginia) increased among young PWID by 114%. In terms of scale of the opioid crisis, recent numbers from SAMHSA indicate that in 2015, 11.8 million people misused prescription opiates or heroin and 2.4 million, or 20%, of those met diagnostic criteria for an opioid use disorder. This leaves millions of people actively using opioids and at risk of overdose and HIV and HCV transmission while not yet engaged in or ready for treatment.