Marijuana drastically shrinks aggressive form of brain cancer, new study finds

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Marijuana drastically shrinks aggressive form of brain cancer, new study finds

24 November 2014

Over the past few years, research has revealed that marijuana can both destroy certain cancer cells and reduce the growth of others. Now, a new study in mice has found that when combined with radiation treatment, cannabis can effectively shrink one of the most aggressive types of brain tumors.

In a paper published Friday in the journal Molecular Cancer Therapies, a team of researchers from St. George's University of London outlined the "dramatic reductions" they observed in high-grade glioma masses, a deadly form of brain cancer, when treated with a combination of radiation and two different marijuana compounds, also known as cannabinoids. In many cases, those tumors shrunk to as low as one-tenth the sizes of those in the control group.

"We've shown that cannabinoids could play a role in treating one of the most aggressive cancers in adults," Dr. Wai Liu, one of the study's lead authors, wrote in an op-ed earlier this week. "The results are promising...it could provide a way of breaking through glioma and saving more lives."

In an email to The Huffington Post, Liu pointed out that while research surrounding marijuana's cancer-fighting properties is nothing new, his team is the first to document its effect on the disease when used alongside radiation. "The results showed that the final effect was superior to the sum of the parts," he said. "Hopefully, these results will support calls for formal trials in humans to test these combinations."

Liu and his colleagues examined mice that had been infected with glioma and subsequently treated with radiation alone or in combination with varying levels of two cannabis compounds: THC, the psychoactive compound associated with the "high" sensation, and CBD, which doesn't produce psychoactive side effects.

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